The absolute configuration of a compound or API is what most of our
customeres are interested to know about.
Our customers request the crystallization of specific polymorphic forms
including non-stoichiometric hydrates/solvates
Our Customers will profit as:
Crystallise! offers fixed prices for their standard services of X-ray
measurement and data analysis. This service includes the tasks from b) - i).
The customer provides Crystallise! single crystals suitable for the
analysis.
Where others have failed to crystallize, Crystallise! has succeeded:
Our most requested service is the crystallization of solid compounds. Where
other companies have tried for many years to produce a single crystal for X-ray
analysis, Crystallise! has succeeded within weeks.
We have produced more than 150 structures of API's from our customers
After 10 years of working for the Pharma industry, we still have some 80-85 %
success on crystallization and > 95 % success on producing a structure.
Special Service: Crystallization
Our track record includes: Poly-peptides, Specific non-stoichiometric
hydrates/solvates, co-crystals/salts, meta-stable polymorphs and many others.
Your Advantage
Although some research facilities in Switzerland have crystallographic
services, they rarely offer the crystallization of samples. Our long
experience in crystallization and the ability to handle any kind of samples,
including air/moisture/temperature unstable substances, is where you will profit
from.
NEW: Crystallization using less than 100 mug of sample
Crystallise! has developed a methodology to crystallize nano-crystals directly on a TEM grid for Electron Diffraction (micro-ED) pursposes).
We have proof of concept for various families of natural products where the amounts provided by the customer were less than 1 mg.
Download here our Application Note
Service: X-ray Measurement
Customer provides Crystallise! AG single crystals in mother liquid. Customer provides Crystallise! AG a rough description of how the crystals were obtained.
The size of your crystalline material is irrelevant. If you have crystalline powders, we can still produce a structure using Electron Diffraction (micro-ED).
Better Service Quality
Our prices are comparable to research facilities in Switzerland.
Crystallise! offers fixed prices for data collection & refinement.
Crystallise! charges for successful analysis, only.
Crystallise! also has access to Synchrotron radiation for micro-crystalline size material (< 0.01 x 0.01 x 0.01 mm^3).
Electron Diffraction
Electron Diffraction (micro-ED) is gaining a lot of momentum as a complementary tool for SC-XRD. Crystallise! led the fundation of Eldico Scientific AG
With Eldico Scientific, we can now tackle any kind of nano-crystalline powders and get the structure as straight forward as in SC-XRD.
Service: Data Analysis
Customer has measured a crystal and has a data set which is still unsolved.
Crystallise! AG spends up to one hour free of charge to analyse the problem of
your data.